Tepotinib Inhibits the Epithelial–Mesenchymal Transition and Tumor Growth of Gastric Cancers by Increasing GSK3β, E-Cadherin, and Mucin 5AC and 6 Levels

Aberrant expression of mucins (MUCs) can promote the epithelial–mesenchymal transition (EMT), which leads to enhanced tumorigenesis. Carcinogenesis-related pathways involving c-MET and β-catenin are associated with MUCs. In this study, we characterized the expression of EMT-relevant proteins includi...

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Detalles Bibliográficos
Autores principales: Sohn, Sung-Hwa, Sul, Hee Jung, Kim, Bohyun, Kim, Bum Jun, Kim, Hyeong Su, Zang, Dae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503648/
https://www.ncbi.nlm.nih.gov/pubmed/32825724
http://dx.doi.org/10.3390/ijms21176027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503648/
https://www.ncbi.nlm.nih.gov/pubmed/32825724
http://dx.doi.org/10.3390/ijms21176027

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