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ApoE Lipidation as a Therapeutic Target in Alzheimer’s Disease
Apolipoprotein E (APOE) is the major cholesterol carrier in the brain, affecting various normal cellular processes including neuronal growth, repair and remodeling of membranes, synaptogenesis, clearance and degradation of amyloid β (Aβ) and neuroinflammation. In humans, the APOE gene has three comm...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503657/ https://www.ncbi.nlm.nih.gov/pubmed/32882843 http://dx.doi.org/10.3390/ijms21176336 |