An Atomic-Level Perspective of HMG-CoA-Reductase: The Target Enzyme to Treat Hypercholesterolemia

This review provides an updated atomic-level perspective regarding the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoAR), linking the more recent data on this enzyme with a structure/function interpretation. This enzyme catalyzes one of the most important steps in cholesterol biosynt...

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Detalles Bibliográficos
Autores principales: Gesto, Diana S., Pereira, Carlos M. S., Cerqueira, Nuno M. F. S., Sousa, Sérgio F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503714/
https://www.ncbi.nlm.nih.gov/pubmed/32859023
http://dx.doi.org/10.3390/molecules25173891