Hepatitis B Virus preS/S Truncation Mutant rtM204I/sW196* Increases Carcinogenesis through Deregulated HIF1A, MGST2, and TGFbi

Inevitable long-term therapy with nucleos(t)ide analogs in patients with chronic hepatitis B virus (HBV) infection has selected reverse-transcriptase (rt) mutants in a substantial proportion of patients. Some of these mutants introduce premature stop codons in the overlapping surface (s) gene, inclu...

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Detalles Bibliográficos
Autores principales: Lai, Ming-Wei, Liang, Kung-Hao, Yeh, Chau-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503731/
https://www.ncbi.nlm.nih.gov/pubmed/32887289
http://dx.doi.org/10.3390/ijms21176366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503731/
https://www.ncbi.nlm.nih.gov/pubmed/32887289
http://dx.doi.org/10.3390/ijms21176366

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