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Genome-wide chromosomal instability by cell-free DNA sequencing predicts survival in patients with metastatic breast cancer
BACKGROUND: Genome-wide chromosomal instability, instead of specific somatic mutations or copy-number alterations in selected genes, is a significant property of cancer and may suggest a new strategy for treatment. Here we utilized cell-free DNA (cfDNA) sequencing to display the whole picture of chr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503795/ https://www.ncbi.nlm.nih.gov/pubmed/32738630 http://dx.doi.org/10.1016/j.breast.2020.07.004 |