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Genome-wide chromosomal instability by cell-free DNA sequencing predicts survival in patients with metastatic breast cancer

BACKGROUND: Genome-wide chromosomal instability, instead of specific somatic mutations or copy-number alterations in selected genes, is a significant property of cancer and may suggest a new strategy for treatment. Here we utilized cell-free DNA (cfDNA) sequencing to display the whole picture of chr...

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Detalles Bibliográficos
Autores principales:	Mo, Hongnan, Wang, Xiaobing, Ma, Fei, Qian, Ziliang, Sun, Xiaoying, Yi, Zongbi, Guan, Xiuwen, Li, Lixi, Liu, Binliang, Xu, Binghe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503795/ https://www.ncbi.nlm.nih.gov/pubmed/32738630 http://dx.doi.org/10.1016/j.breast.2020.07.004

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