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Trichostatin A Alleviates Renal Interstitial Fibrosis Through Modulation of the M2 Macrophage Subpopulation

Mounting evidence indicates that an increase in histone deacetylation contributes to renal fibrosis. Although inhibition of histone deacetylase (HDAC) can reduce the extent of fibrosis, whether HDAC inhibitors exert the antifibrotic effect through modulating the phenotypes of macrophages, the key re...

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Detalles Bibliográficos
Autores principales: Tseng, Wei-Cheng, Tsai, Ming-Tsun, Chen, Nien-Jung, Tarng, Der-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503910/
https://www.ncbi.nlm.nih.gov/pubmed/32825118
http://dx.doi.org/10.3390/ijms21175966