Ameliorated Autoimmune Arthritis and Impaired B Cell Receptor-Mediated Ca(2+) Influx in Nkx2-3 Knock-out Mice

B cells play a crucial role in the pathogenesis of rheumatoid arthritis. In Nkx2-3-deficient mice (Nkx2-3(−/−)) the spleen’s histological structure is fundamentally changed; therefore, B cell homeostasis is seriously disturbed. Based on this, we were curious, whether autoimmune arthritis could be in...

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Detalles Bibliográficos
Autores principales: Khanfar, Esam, Olasz, Katalin, Gábris, Fanni, Gajdócsi, Erzsébet, Botz, Bálint, Kiss, Tamás, Kugyelka, Réka, Berki, Tímea, Balogh, Péter, Boldizsár, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503974/
https://www.ncbi.nlm.nih.gov/pubmed/32859051
http://dx.doi.org/10.3390/ijms21176162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7503974/
https://www.ncbi.nlm.nih.gov/pubmed/32859051
http://dx.doi.org/10.3390/ijms21176162

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