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Novel Therapeutic Application of Self-Assembly Peptides Targeting the Mitochondria in In Vitro and In Vivo Experimental Models of Gastric Cancer

Here, we provide the possibility of a novel chemotherapeutic agent against gastric cancer cells, comprising the combination of 5-fluorouracil (5-FU) and a mitochondria-targeting self-assembly peptide, which is a phenylalanine dipeptide with triphenyl phosphonium (Mito-FF). The anticancer effects and...

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Detalles Bibliográficos
Autores principales: Kim, Dong Jin, Jeena, M. T., Kim, Ok-Hee, Hong, Ha-Eun, Seo, Haeyeon, Ryu, Ja-Hyoung, Kim, Say-June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504046/
https://www.ncbi.nlm.nih.gov/pubmed/32854415
http://dx.doi.org/10.3390/ijms21176126