Cargando…
Novel Therapeutic Application of Self-Assembly Peptides Targeting the Mitochondria in In Vitro and In Vivo Experimental Models of Gastric Cancer
Here, we provide the possibility of a novel chemotherapeutic agent against gastric cancer cells, comprising the combination of 5-fluorouracil (5-FU) and a mitochondria-targeting self-assembly peptide, which is a phenylalanine dipeptide with triphenyl phosphonium (Mito-FF). The anticancer effects and...
Autores principales: | Kim, Dong Jin, Jeena, M. T., Kim, Ok-Hee, Hong, Ha-Eun, Seo, Haeyeon, Ryu, Ja-Hyoung, Kim, Say-June |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504046/ https://www.ncbi.nlm.nih.gov/pubmed/32854415 http://dx.doi.org/10.3390/ijms21176126 |
Ejemplares similares
-
Application of self-assembly peptides targeting the mitochondria as a novel treatment for sorafenib-resistant hepatocellular carcinoma cells
por: Hong, Tae Ho, et al.
Publicado: (2021) -
Mitochondria localization induced self-assembly of peptide amphiphiles for cellular dysfunction
por: Jeena, M. T., et al.
Publicado: (2017) -
Cancer-mitochondria-targeted photodynamic therapy with supramolecular assembly of HA and a water soluble NIR cyanine dye
por: Thomas, Ajesh P., et al.
Publicado: (2017) -
Enzyme-instructed morphology transformation of mitochondria-targeting peptide for the selective eradication of osteosarcoma
por: Jeena, M. T., et al.
Publicado: (2022) -
Combining Everolimus and Ku0063794 Promotes Apoptosis of Hepatocellular Carcinoma Cells via Reduced Autophagy Resulting from Diminished Expression of miR-4790-3p
por: Choi, Ho Joong, et al.
Publicado: (2021)