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The Lysine Specific Demethylase-1 Negatively Regulates the COL9A1 Gene in Human Articular Chondrocytes

Osteoarthritis (OA) is a degenerative disease of the joints which is associated with an impaired production of the cartilage matrix by the chondrocytes. Here, we investigated the role of Lysine-Specific Demethylase-1 (LSD1), a chromatin remodeling enzyme whose role in articular chondrocytes was prev...

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Detalles Bibliográficos
Autores principales: Durand, Anne-Laure, Dufour, Alexandre, Aubert-Foucher, Elisabeth, Oger-Desfeux, Christine, Pasdeloup, Marielle, Lustig, Sebastien, Servien, Elvire, Vaz, Gualter, Perrier-Groult, Emeline, Mallein-Gerin, Frederic, Lafont, Jerome E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504057/
https://www.ncbi.nlm.nih.gov/pubmed/32878268
http://dx.doi.org/10.3390/ijms21176322