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Asymmetric Conservation within Pairs of Co-Occurred Motifs Mediates Weak Direct Binding of Transcription Factors in ChIP-Seq Data

(1) Background: Transcription factors (TFs) are main regulators of eukaryotic gene expression. The cooperative binding to genomic DNA of at least two TFs is the widespread mechanism of transcription regulation. Cooperating TFs can be revealed through the analysis of co-occurrence of their motifs. (2...

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Detalles Bibliográficos
Autores principales: Levitsky, Victor, Oshchepkov, Dmitry, Zemlyanskaya, Elena, Merkulova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504069/
https://www.ncbi.nlm.nih.gov/pubmed/32825662
http://dx.doi.org/10.3390/ijms21176023