5-(N-Trifluoromethylcarboxy)aminouracil as a Potential DNA Radiosensitizer and Its Radiochemical Conversion into N-Uracil-5-yloxamic Acid

Hypoxia—a hallmark of solid tumors—dramatically impairs radiotherapy, one of the most common anticancer modalities. The adverse effect of the low-oxygen state can be eliminated by the concomitant use of a hypoxic cell radiosensitizer. In the present paper, we show that 5-(N-trifluoromethylcarboxy) a...

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Detalles Bibliográficos
Autores principales: Spisz, Paulina, Kozak, Witold, Chomicz-Mańka, Lidia, Makurat, Samanta, Falkiewicz, Karina, Sikorski, Artur, Czaja, Anna, Rak, Janusz, Zdrowowicz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504071/
https://www.ncbi.nlm.nih.gov/pubmed/32883013
http://dx.doi.org/10.3390/ijms21176352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504071/
https://www.ncbi.nlm.nih.gov/pubmed/32883013
http://dx.doi.org/10.3390/ijms21176352

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