Cell Bank Origin of MDCK Parental Cells Shapes Adaptation to Serum-Free Suspension Culture and Canine Adenoviral Vector Production

Phenotypic variation in cultured mammalian cell lines is known to be induced by passaging and culture conditions. Yet, the effect these variations have on the production of viral vectors has been overlooked. In this work we evaluated the impact of using Madin–Darby canine kidney (MDCK) parental cell...

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Detalles Bibliográficos
Autores principales: Rodrigues, Ana Filipa, Fernandes, Paulo, Laske, Tanja, Castro, Rute, Alves, Paula Marques, Genzel, Yvonne, Coroadinha, Ana Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504089/
https://www.ncbi.nlm.nih.gov/pubmed/32854295
http://dx.doi.org/10.3390/ijms21176111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504089/
https://www.ncbi.nlm.nih.gov/pubmed/32854295
http://dx.doi.org/10.3390/ijms21176111

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