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Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress

Selective autolysosomal degradation of damaged mitochondria, also called mitophagy, is an indispensable process for maintaining integrity and homeostasis of mitochondria. One well-established mechanism mediating selective removal of mitochondria under relatively mild mitochondria-depolarizing stress...

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Detalles Bibliográficos
Autores principales: Kim, Heejeong, Jeon, Byeong Tak, Kim, Isaac M., Bennett, Sydney J., Lorch, Carolyn M., Viana, Martonio Ponte, Myers, Jacob F., Trupp, Caroline J., Whipps, Zachary T., Kundu, Mondira, Chung, Soonkyu, Sun, Xinghui, Khalimonchuk, Oleh, Lee, Jaekwon, Ro, Seung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504119/
https://www.ncbi.nlm.nih.gov/pubmed/32854424
http://dx.doi.org/10.3390/ijms21176130