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Sestrin2 Phosphorylation by ULK1 Induces Autophagic Degradation of Mitochondria Damaged by Copper-Induced Oxidative Stress
Selective autolysosomal degradation of damaged mitochondria, also called mitophagy, is an indispensable process for maintaining integrity and homeostasis of mitochondria. One well-established mechanism mediating selective removal of mitochondria under relatively mild mitochondria-depolarizing stress...
Autores principales: | Kim, Heejeong, Jeon, Byeong Tak, Kim, Isaac M., Bennett, Sydney J., Lorch, Carolyn M., Viana, Martonio Ponte, Myers, Jacob F., Trupp, Caroline J., Whipps, Zachary T., Kundu, Mondira, Chung, Soonkyu, Sun, Xinghui, Khalimonchuk, Oleh, Lee, Jaekwon, Ro, Seung-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504119/ https://www.ncbi.nlm.nih.gov/pubmed/32854424 http://dx.doi.org/10.3390/ijms21176130 |
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