Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from Glycyrrhiza uralensis

Eight compounds were isolated from the roots of Glycyrrhiza uralensis and tested for cholinesterase (ChE) and monoamine oxidase (MAO) inhibitory activities. The coumarin glycyrol (GC) effectively inhibited butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) with IC(50) values of 7.22 and 14...

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Detalles Bibliográficos
Autores principales: Jeong, Geum Seok, Kang, Myung-Gyun, Lee, Joon Yeop, Lee, Sang Ryong, Park, Daeui, Cho, MyoungLae, Kim, Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504216/
https://www.ncbi.nlm.nih.gov/pubmed/32859055
http://dx.doi.org/10.3390/molecules25173896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504216/
https://www.ncbi.nlm.nih.gov/pubmed/32859055
http://dx.doi.org/10.3390/molecules25173896

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