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Inhibition of Butyrylcholinesterase and Human Monoamine Oxidase-B by the Coumarin Glycyrol and Liquiritigenin Isolated from Glycyrrhiza uralensis
Eight compounds were isolated from the roots of Glycyrrhiza uralensis and tested for cholinesterase (ChE) and monoamine oxidase (MAO) inhibitory activities. The coumarin glycyrol (GC) effectively inhibited butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) with IC(50) values of 7.22 and 14...
Autores principales: | Jeong, Geum Seok, Kang, Myung-Gyun, Lee, Joon Yeop, Lee, Sang Ryong, Park, Daeui, Cho, MyoungLae, Kim, Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504216/ https://www.ncbi.nlm.nih.gov/pubmed/32859055 http://dx.doi.org/10.3390/molecules25173896 |
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