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Umbilical Cord Mesenchymal Stem Cell-Derived Nanovesicles Potentiate the Bone-Formation Efficacy of Bone Morphogenetic Protein 2

Recombinant human bone morphogenetic protein 2 (rhBMP-2) is one of the most potent osteogenic factors used to treat bone loss. However, at higher doses, rhBMP-2 does not necessarily increase bone formation but rather increases the incidence of adverse side effects. Here, we investigated whether umbi...

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Detalles Bibliográficos
Autores principales: Lim, Songhyun, Lyu, Hao-Zhen, Lee, Ju-Ro, Han, Shi Huan, Lee, Jae Hyup, Kim, Byung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504262/
https://www.ncbi.nlm.nih.gov/pubmed/32899307
http://dx.doi.org/10.3390/ijms21176425