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Stochastic Reaction–Diffusion Model of the Binding of Monoclonal Antibodies to CD4 Receptors on the Surface of T Cells

A stochastic reaction–diffusion model was developed to describe the binding of labeled monoclonal antibodies (mAbs) to CD4 receptors on the surface of T cells. The mAbs diffused to, adsorbed on, and underwent monovalent and bivalent binding to CD4 receptors on the cell surface. The model predicted t...

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Detalles Bibliográficos
Autores principales: Wang, Lili, DeRose, Paul C., Inwood, Sarah L., Gaigalas, Adolfas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504294/
https://www.ncbi.nlm.nih.gov/pubmed/32846978
http://dx.doi.org/10.3390/ijms21176086