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GANT61 and Lithium Chloride Inhibit the Growth of Head and Neck Cancer Cell Lines Through the Regulation of GLI3 Processing by GSK3β

Several signaling pathways are aberrantly activated in head and neck squamous cell carcinoma (HNSCC), including the Hedgehog-Gli (HH-GLI), WNT, EGFR, and NOTCH pathways. The HH-GLI pathway has mostly been investigated in the context of canonical signal transduction and the inhibition of the membrane...

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Detalles Bibliográficos
Autores principales: Zubčić, Vedran, Rinčić, Nikolina, Kurtović, Matea, Trnski, Diana, Musani, Vesna, Ozretić, Petar, Levanat, Sonja, Leović, Dinko, Sabol, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504345/
https://www.ncbi.nlm.nih.gov/pubmed/32899202
http://dx.doi.org/10.3390/ijms21176410