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In Silico Identification of Potential Natural Product Inhibitors of Human Proteases Key to SARS-CoV-2 Infection

Presently, there are no approved drugs or vaccines to treat COVID-19, which has spread to over 200 countries and at the time of writing was responsible for over 650,000 deaths worldwide. Recent studies have shown that two human proteases, TMPRSS2 and cathepsin L, play a key role in host cell entry o...

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Detalles Bibliográficos
Autores principales: Vivek-Ananth, R.P., Rana, Abhijit, Rajan, Nithin, Biswal, Himansu S., Samal, Areejit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504347/
https://www.ncbi.nlm.nih.gov/pubmed/32842606
http://dx.doi.org/10.3390/molecules25173822