Synthesis, In Silico and In Vitro Evaluation for Acetylcholinesterase and BACE-1 Inhibitory Activity of Some N-Substituted-4-Phenothiazine-Chalcones

Acetylcholinesterase (AChE) and beta-secretase (BACE-1) are two attractive targets in the discovery of novel substances that could control multiple aspects of Alzheimer’s disease (AD). Chalcones are the flavonoid derivatives with diverse bioactivities, including AChE and BACE-1 inhibition. In this s...

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Detalles Bibliográficos
Autores principales: Tran, Thai-Son, Le, Minh-Tri, Nguyen, Thi-Cam-Vi, Tran, The-Huan, Tran, Thanh-Dao, Thai, Khac-Minh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504348/
https://www.ncbi.nlm.nih.gov/pubmed/32867308
http://dx.doi.org/10.3390/molecules25173916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504348/
https://www.ncbi.nlm.nih.gov/pubmed/32867308
http://dx.doi.org/10.3390/molecules25173916

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