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Synthesis, In Silico and In Vitro Evaluation for Acetylcholinesterase and BACE-1 Inhibitory Activity of Some N-Substituted-4-Phenothiazine-Chalcones
Acetylcholinesterase (AChE) and beta-secretase (BACE-1) are two attractive targets in the discovery of novel substances that could control multiple aspects of Alzheimer’s disease (AD). Chalcones are the flavonoid derivatives with diverse bioactivities, including AChE and BACE-1 inhibition. In this s...
Autores principales: | Tran, Thai-Son, Le, Minh-Tri, Nguyen, Thi-Cam-Vi, Tran, The-Huan, Tran, Thanh-Dao, Thai, Khac-Minh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504348/ https://www.ncbi.nlm.nih.gov/pubmed/32867308 http://dx.doi.org/10.3390/molecules25173916 |
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