Insight into the Folding and Dimerization Mechanisms of the N-Terminal Domain from Human TDP-43

TAR DNA-binding protein 43 (TDP-43) is a 414-residue long nuclear protein whose deposition into intraneuronal insoluble inclusions has been associated with the onset of amyotrophic lateral sclerosis (ALS) and other diseases. This protein is physiologically a homodimer, and dimerization occurs throug...

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Detalles Bibliográficos
Autores principales: Vivoli-Vega, Mirella, Guri, Prandvera, Chiti, Fabrizio, Bemporad, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504384/
https://www.ncbi.nlm.nih.gov/pubmed/32872449
http://dx.doi.org/10.3390/ijms21176259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504384/
https://www.ncbi.nlm.nih.gov/pubmed/32872449
http://dx.doi.org/10.3390/ijms21176259

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