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Learning from Monocyte-Macrophage Fusion and Multinucleation: Potential Therapeutic Targets for Osteoporosis and Rheumatoid Arthritis

Excessive bone resorption by osteoclasts (OCs) covers an essential role in developing bone diseases, such as osteoporosis (OP) and rheumatoid arthritis (RA). Monocytes or macrophages fusion and multinucleation (M-FM) are key processes for generating multinucleated mature cells with essential roles i...

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Detalles Bibliográficos
Autores principales: Gambari, Laura, Grassi, Francesco, Roseti, Livia, Grigolo, Brunella, Desando, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504439/
https://www.ncbi.nlm.nih.gov/pubmed/32825443
http://dx.doi.org/10.3390/ijms21176001