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Learning from Monocyte-Macrophage Fusion and Multinucleation: Potential Therapeutic Targets for Osteoporosis and Rheumatoid Arthritis
Excessive bone resorption by osteoclasts (OCs) covers an essential role in developing bone diseases, such as osteoporosis (OP) and rheumatoid arthritis (RA). Monocytes or macrophages fusion and multinucleation (M-FM) are key processes for generating multinucleated mature cells with essential roles i...
Autores principales: | Gambari, Laura, Grassi, Francesco, Roseti, Livia, Grigolo, Brunella, Desando, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504439/ https://www.ncbi.nlm.nih.gov/pubmed/32825443 http://dx.doi.org/10.3390/ijms21176001 |
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