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Improved Autophagic Flux in Escapers from Doxorubicin-Induced Senescence/Polyploidy of Breast Cancer Cells

The induction of senescence/polyploidization and their role in cancer recurrence is still a poorly explored issue. We showed that MDA-MB-231 and MCF-7 breast cancer cells underwent reversible senescence/polyploidization upon pulse treatment with doxorubicin (dox). Subsequently, senescent/polyploid c...

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Detalles Bibliográficos
Autores principales: Bojko, Agnieszka, Staniak, Karolina, Czarnecka-Herok, Joanna, Sunderland, Piotr, Dudkowska, Magdalena, Śliwińska, Małgorzata Alicja, Salmina, Kristine, Sikora, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504443/
https://www.ncbi.nlm.nih.gov/pubmed/32846959
http://dx.doi.org/10.3390/ijms21176084