Ecto-Nucleotide Triphosphate Diphosphohydrolase-2 (NTPDase2) Deletion Increases Acetaminophen-Induced Hepatotoxicity

Ecto-nucleotidase triphosphate diphosphohydrolase-2 (NTPDase2) is an ecto-enzyme that is expressed on portal fibroblasts in the liver that modulates P2 receptor signaling by regulating local concentrations of extracellular ATP and ADP. NTPDase2 has protective properties in liver fibrosis and may imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Feldbrügge, Linda, Splith, Katrin, Kämmerer, Ines, Richter, Sandra, Riddermann, Anna, Ortiz Galindo, Santiago Andres, Krenzien, Felix, Müller, Tobias, Csizmadia, Eva, Pratschke, Johann, Robson, Simon C., Schmelzle, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504458/
https://www.ncbi.nlm.nih.gov/pubmed/32825435
http://dx.doi.org/10.3390/ijms21175998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504458/
https://www.ncbi.nlm.nih.gov/pubmed/32825435
http://dx.doi.org/10.3390/ijms21175998

Ejemplares similares