Biased versus Partial Agonism in the Search for Safer Opioid Analgesics

Opioids such as morphine—acting at the mu opioid receptor—are the mainstay for treatment of moderate to severe pain and have good efficacy in these indications. However, these drugs produce a plethora of unwanted adverse effects including respiratory depression, constipation, immune suppression and...

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Detalles Bibliográficos
Autores principales: Azevedo Neto, Joaquim, Costanzini, Anna, De Giorgio, Roberto, Lambert, David G., Ruzza, Chiara, Calò, Girolamo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504468/
https://www.ncbi.nlm.nih.gov/pubmed/32854452
http://dx.doi.org/10.3390/molecules25173870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504468/
https://www.ncbi.nlm.nih.gov/pubmed/32854452
http://dx.doi.org/10.3390/molecules25173870

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