Cargando…

Anti-Metastatic Activity of an Anti-EGFR Monoclonal Antibody against Metastatic Colorectal Cancer with KRAS p.G13D Mutation

The now clinically-used anti-epidermal growth factor receptor (EGFR) monoclonal antibodies have demonstrated significant efficacy only in patients with metastatic colorectal cancer (mCRC), with wild-type Kirsten rat sarcoma viral oncogene homolog (KRAS). However, no effective treatments for patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohishi, Tomokazu, Kato, Yukinari, Kaneko, Mika K., Ohba, Shun-ichi, Inoue, Hiroyuki, Harakawa, Akiko, Kawada, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504481/
https://www.ncbi.nlm.nih.gov/pubmed/32839411
http://dx.doi.org/10.3390/ijms21176037