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Biosynthesized Multivalent Lacritin Peptides Stimulate Exosome Production in Human Corneal Epithelium

Lacripep is a therapeutic peptide derived from the human tear protein, Lacritin. Lacripep interacts with syndecan-1 and induces mitogenesis upon the removal of heparan sulfates (HS) that are attached at the extracellular domain of syndecan-1. The presence of HS is a prerequisite for the syndecan-1 c...

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Detalles Bibliográficos
Autores principales: Lee, Changrim, Edman, Maria C., Laurie, Gordon W., Hamm-Alvarez, Sarah F., MacKay, J. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504496/
https://www.ncbi.nlm.nih.gov/pubmed/32859014
http://dx.doi.org/10.3390/ijms21176157