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ADAR1 Suppresses Interferon Signaling in Gastric Cancer Cells by MicroRNA-302a-Mediated IRF9/STAT1 Regulation

ADAR (adenosine deaminase acting on RNA) catalyzes the deamination of adenosine to generate inosine, through its binding to double-stranded RNA (dsRNA), a phenomenon known as RNA editing. One of the functions of ADAR1 is suppressing the type I interferon (IFN) response, but its mechanism in gastric...

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Detalles Bibliográficos
Autores principales: Jiang, Lushang, Park, Min Ji, Cho, Charles J., Lee, Kihak, Jung, Min Kyo, Pack, Chan Gi, Myung, Seung-Jae, Chang, Suhwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504523/
https://www.ncbi.nlm.nih.gov/pubmed/32867271
http://dx.doi.org/10.3390/ijms21176195