Heart Failure Disturbs Gut–Blood Barrier and Increases Plasma Trimethylamine, a Toxic Bacterial Metabolite

Trimethylamine (TMA) is a gut bacteria product oxidized by the liver to trimethylamine-N-oxide (TMAO). Clinical evidence suggests that cardiovascular disease is associated with increased plasma TMAO. However, little headway has been made in understanding this relationship on a mechanistic and molecu...

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Detalles Bibliográficos
Autores principales: Drapala, Adrian, Szudzik, Mateusz, Chabowski, Dawid, Mogilnicka, Izabella, Jaworska, Kinga, Kraszewska, Katarzyna, Samborowska, Emilia, Ufnal, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504565/
https://www.ncbi.nlm.nih.gov/pubmed/32859047
http://dx.doi.org/10.3390/ijms21176161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504565/
https://www.ncbi.nlm.nih.gov/pubmed/32859047
http://dx.doi.org/10.3390/ijms21176161

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