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Tumor Necrosis Factor α Influences Phenotypic Plasticity and Promotes Epigenetic Changes in Human Basal Forebrain Cholinergic Neuroblasts

TNFα is the main proinflammatory cytokine implicated in the pathogenesis of neurodegenerative disorders, but it also modulates physiological functions in both the developing and adult brain. In this study, we investigated a potential direct role of TNFα in determining phenotypic changes of a recentl...

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Detalles Bibliográficos
Autores principales: Guarnieri, Giulia, Sarchielli, Erica, Comeglio, Paolo, Herrera-Puerta, Erika, Piaceri, Irene, Nacmias, Benedetta, Benelli, Matteo, Kelsey, Gavin, Maggi, Mario, Gallina, Pasquale, Vannelli, Gabriella Barbara, Morelli, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504606/
https://www.ncbi.nlm.nih.gov/pubmed/32854421
http://dx.doi.org/10.3390/ijms21176128