Adenovirus-Mediated FasL Minigene Transfer Endows Transduced Cells with Killer Potential

Fas ligand (First apoptosis signal ligand, FasL, also known as CD95L) is the common executioner of apoptosis within the tumor necrosis factor (TNF) superfamily. We aimed to induce functional FasL expression in transduced cells using an adenovirus vector, which has the advantage of strong and transie...

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Detalles Bibliográficos
Autores principales: Dumitrescu, Madalina, Trusca, Violeta Georgeta, Savu, Lorand, Stancu, Ioana Georgeta, Ratiu, Attila Cristian, Simionescu, Maya, Gafencu, Anca Violeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504687/
https://www.ncbi.nlm.nih.gov/pubmed/32825521
http://dx.doi.org/10.3390/ijms21176011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504687/
https://www.ncbi.nlm.nih.gov/pubmed/32825521
http://dx.doi.org/10.3390/ijms21176011

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