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CDK4/6 Inhibitors in Breast Cancer Treatment: Potential Interactions with Drug, Gene, and Pathophysiological Conditions

Palbociclib, ribociclib, and abemaciclib belong to the third generation of cyclin-dependent kinases inhibitors (CDKis), an established therapeutic class for advanced and metastatic breast cancer. Interindividual variability in the therapeutic response of CDKis has been reported and some individuals...

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Detalles Bibliográficos
Autores principales: Roncato, Rossana, Angelini, Jacopo, Pani, Arianna, Cecchin, Erika, Sartore-Bianchi, Andrea, Siena, Salvatore, De Mattia, Elena, Scaglione, Francesco, Toffoli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504705/
https://www.ncbi.nlm.nih.gov/pubmed/32883002
http://dx.doi.org/10.3390/ijms21176350