Neuroprotection of Retinal Ganglion Cells with AAV2-BDNF Pretreatment Restoring Normal TrkB Receptor Protein Levels in Glaucoma

Intravitreal delivery of brain-derived neurotrophic factor (BDNF) by injection of recombinant protein or by gene therapy can alleviate retinal ganglion cell (RGC) loss after optic nerve injury (ONI) or laser-induced ocular hypertension (OHT). In models of glaucoma, BDNF therapy can delay or halt RGC...

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Detalles Bibliográficos
Autores principales: Wójcik-Gryciuk, Anna, Gajewska-Woźniak, Olga, Kordecka, Katarzyna, Boguszewski, Paweł M., Waleszczyk, Wioletta, Skup, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504711/
https://www.ncbi.nlm.nih.gov/pubmed/32872441
http://dx.doi.org/10.3390/ijms21176262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504711/
https://www.ncbi.nlm.nih.gov/pubmed/32872441
http://dx.doi.org/10.3390/ijms21176262

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