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Automated Synthesis of Fluorine-18 Labeled CXCR4 Ligand via the Conjugation with Nicotinic Acid N-Hydroxysuccinimide Ester (6-[(18)F]SFPy)

The C-X-C motif chemokine receptor 4 (CXCR4) is a seven-transmembrane G protein-coupled receptor that is overexpressed in numerous diseases, particularly in various cancers and is a powerful chemokine, attracting cells to the bone marrow niche. Therefore, CXCR4 is an attractive target for imaging an...

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Detalles Bibliográficos
Autores principales: Basuli, Falguni, Zhang, Xiang, Phelps, Tim E., Jagoda, Elaine M., Choyke, Peter L., Swenson, Rolf E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504725/
https://www.ncbi.nlm.nih.gov/pubmed/32867358
http://dx.doi.org/10.3390/molecules25173924