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Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease

Memantine (3,5-dimethyladamantan-1-amine) is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist approved for treatment of moderate-to-severe Alzheimer’s disease (AD), a neurodegenerative condition characterized by a progressive cognitive decline. Unfortunately, memanti...

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Detalles Bibliográficos
Autores principales: Marotta, Giambattista, Basagni, Filippo, Rosini, Michela, Minarini, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504780/
https://www.ncbi.nlm.nih.gov/pubmed/32887400
http://dx.doi.org/10.3390/molecules25174005