Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry

Peptidyl fluoromethyl ketones occupy a pivotal role in the current scenario of synthetic chemistry, thanks to their numerous applications as inhibitors of hydrolytic enzymes. The insertion of one or more fluorine atoms adjacent to a C-terminal ketone moiety greatly modifies the physicochemical prope...

Descripción completa

Detalles Bibliográficos
Autores principales: Citarella, Andrea, Micale, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504820/
https://www.ncbi.nlm.nih.gov/pubmed/32899354
http://dx.doi.org/10.3390/molecules25174031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504820/
https://www.ncbi.nlm.nih.gov/pubmed/32899354
http://dx.doi.org/10.3390/molecules25174031

Ejemplares similares