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Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry
Peptidyl fluoromethyl ketones occupy a pivotal role in the current scenario of synthetic chemistry, thanks to their numerous applications as inhibitors of hydrolytic enzymes. The insertion of one or more fluorine atoms adjacent to a C-terminal ketone moiety greatly modifies the physicochemical prope...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504820/ https://www.ncbi.nlm.nih.gov/pubmed/32899354 http://dx.doi.org/10.3390/molecules25174031 |