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Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNS
BACKGROUND: Microglia, the primary resident myeloid cells of the brain, play critical roles in immune defense by maintaining tissue homeostasis and responding to injury or disease. However, microglial activation and dysfunction has been implicated in a number of central nervous system (CNS) disorder...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504855/ https://www.ncbi.nlm.nih.gov/pubmed/32951604 http://dx.doi.org/10.1186/s12974-020-01931-0 |