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A near-infrared fluorogenic dimer enables background-free imaging of endogenous GPCRs in living mice
Fluorescent probes are commonly used in studying G protein-coupled receptors in living cells; however their application to the whole animal receptor imaging is still challenging. To address this problem, we report the design and the synthesis of the first near-infrared emitting fluorogenic dimer wit...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504901/ https://www.ncbi.nlm.nih.gov/pubmed/33033597 http://dx.doi.org/10.1039/d0sc01018a |