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A near-infrared fluorogenic dimer enables background-free imaging of endogenous GPCRs in living mice

Fluorescent probes are commonly used in studying G protein-coupled receptors in living cells; however their application to the whole animal receptor imaging is still challenging. To address this problem, we report the design and the synthesis of the first near-infrared emitting fluorogenic dimer wit...

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Detalles Bibliográficos
Autores principales: Esteoulle, Lucie, Daubeuf, François, Collot, Mayeul, Riché, Stéphanie, Durroux, Thierry, Brasse, David, Marchand, Patrice, Karpenko, Julie, Klymchenko, Andrey S., Bonnet, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504901/
https://www.ncbi.nlm.nih.gov/pubmed/33033597
http://dx.doi.org/10.1039/d0sc01018a