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Multiple Ehrlichia chaffeensis Genes Critical for Its Persistent Infection in a Vertebrate Host Are Identified by Random Mutagenesis Coupled with In Vivo Infection Assessment

Ehrlichia chaffeensis, a tick-transmitted obligate intracellular rickettsial agent, causes human monocytic ehrlichiosis. In recent reports, we described substantial advances in developing random and targeted gene disruption methods to investigate the functions of E. chaffeensis genes. We reported ea...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Nair, Arathy D. S., Alhassan, Andy, Jaworski, Deborah C., Liu, Huitao, Trinkl, Kathleen, Hove, Paidashe, Ganta, Charan K., Burkhardt, Nicole, Munderloh, Ulrike G., Ganta, Roman R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504954/
https://www.ncbi.nlm.nih.gov/pubmed/32747600
http://dx.doi.org/10.1128/IAI.00316-20