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GR silencing impedes the progression of castration-resistant prostate cancer through the JAG1/NOTCH2 pathway via up-regulation of microRNA-143-3p

BACKGROUND: Despite notable progression from a therapeutic point of view, castration resistant prostate cancer (CRPC) remains a clinical significant stumbling block. The current study aimed to elucidate the functional role of the gene glucocorticoid receptor (GR) in CRPC, and identify the contributi...

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Detalles Bibliográficos
Autores principales: Zhang, Linshen, Jiang, Hongjun, Zhang, Yufan, Wang, Chenrong, Xia, Xixi, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505006/
https://www.ncbi.nlm.nih.gov/pubmed/32568179
http://dx.doi.org/10.3233/CBM-191271