Cargando…

GR silencing impedes the progression of castration-resistant prostate cancer through the JAG1/NOTCH2 pathway via up-regulation of microRNA-143-3p

BACKGROUND: Despite notable progression from a therapeutic point of view, castration resistant prostate cancer (CRPC) remains a clinical significant stumbling block. The current study aimed to elucidate the functional role of the gene glucocorticoid receptor (GR) in CRPC, and identify the contributi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Linshen, Jiang, Hongjun, Zhang, Yufan, Wang, Chenrong, Xia, Xixi, Sun, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505006/ https://www.ncbi.nlm.nih.gov/pubmed/32568179 http://dx.doi.org/10.3233/CBM-191271

Ejemplares similares

Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer
por: Liu, Michelle X., et al.
Publicado: (2013)

Silencing microRNA-143 protects the integrity of the blood-brain barrier: implications for methamphetamine abuse
por: Bai, Ying, et al.
Publicado: (2016)

NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma
por: Fiaschetti, Giulio, et al.
Publicado: (2014)

MicroRNA-539 inhibits the progression of Wilms’ Tumor through downregulation of JAG1 and Notch1/3
por: Su, Hailong, et al.
Publicado: (2019)

JAG1-NOTCH4 mechanosensing drives atherosclerosis
por: Souilhol, Celine, et al.
Publicado: (2022)

Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL()()
por: Pelullo, Maria, et al.
Publicado: (2014)

The role of Notch ligand Jagged1 in osteosarcoma proliferation, metastasis, and recurrence
por: Zhang, Jianping, et al.
Publicado: (2021)

Sex-specific involvement of the Notch–JAG pathway in social recognition
por: Jaaro-Peled, Hanna, et al.
Publicado: (2022)

Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer
por: Dai, Y, et al.
Publicado: (2014)

MicroRNA-26a and -26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway
por: Chen, Xiaoyun, et al.
Publicado: (2017)

MicroRNA-26a and -26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway
por: Chen, Xiaoyun, et al.
Publicado: (2017)

Molecular Basis for Jagged-1/Serrate Ligand Recognition by the Notch Receptor
por: Whiteman, Pat, et al.
Publicado: (2013)

The Notch Ligand Jagged1 as a Target for Anti-Tumor Therapy
por: Li, Demin, et al.
Publicado: (2014)

MicroRNA-143/-145 in Cardiovascular Diseases
por: Zhao, Wang, et al.
Publicado: (2015)

MicroRNA-143 expression inhibits the growth and the invasion of osteosarcoma
por: Zhang, Pei, et al.
Publicado: (2022)

Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes
por: Sekine, Chiyoko, et al.
Publicado: (2012)

Leptin modulated microRNA-628-5p targets Jagged-1 and inhibits prostate cancer hallmarks
por: Rios-Colon, Leslimar, et al.
Publicado: (2022)

MicroRNA miR-214-5p induces senescence of microvascular endothelial cells by targeting the JAG1/Notch signaling pathway
por: Jo, Hye-ram, et al.
Publicado: (2023)

Novel scFv against Notch Ligand JAG1 Suitable for Development of Cell Therapies toward JAG1-Positive Tumors
por: Silva, Gabriela, et al.
Publicado: (2023)

The differential expression of microRNA-143,145 in endometriosis
por: Zheng, Bingbing, et al.
Publicado: (2014)

MicroRNA‐199b Modulates Vascular Cell Fate During iPS Cell Differentiation by Targeting the Notch Ligand Jagged1 and Enhancing VEGF Signaling
por: Chen, Ting, et al.
Publicado: (2015)

Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice
por: Nakano, Yasuhiro, et al.
Publicado: (2022)

Decreased circulating microRNA-21 and microRNA-143 are associated to pulmonary hypertension
por: DÜZGÜN, Zekeriya, et al.
Publicado: (2022)

The Notch Ligand JAG1 Is Required for Sensory Progenitor Development in the Mammalian Inner Ear
por: Kiernan, Amy E, et al.
Publicado: (2006)

Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation
por: Jaleco, Ana C., et al.
Publicado: (2001)

Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans
por: Che, L, et al.
Publicado: (2016)

Jagged1-induced Notch activation contributes to the acquisition of bortezomib resistance in myeloma cells
por: Muguruma, Yukari, et al.
Publicado: (2017)

Intraoperative delivery of the Notch ligand Jagged-1 regenerates appendicular and craniofacial bone defects
por: Youngstrom, Daniel W., et al.
Publicado: (2017)

Notch ligand Jagged1 promotes mesenchymal stromal cell-based cartilage repair
por: Sun, Junkui, et al.
Publicado: (2018)

Notch Signaling Ligand Jagged1 Enhances Macrophage-Mediated Response to Helicobacter pylori
por: Wen, Junjie, et al.
Publicado: (2021)

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency
por: Dave, Jui M., et al.
Publicado: (2022)

Determination of Blood NOTCH3 Extracellular Domain and Jagged-1 Levels in Healthy Subjects
por: Kim, Hyesung, et al.
Publicado: (2022)

Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development
por: Xu, Xiaochan, et al.
Publicado: (2023)

MicroRNA determinants of neuroendocrine differentiation in metastatic castration-resistant prostate cancer
por: Bhagirath, Divya, et al.
Publicado: (2020)

Regulation of γδT17 cells by Mycobacterium vaccae through interference with Notch/Jagged1 signaling pathway
por: Yao, Yi En, et al.
Publicado: (2020)

MicroRNA-936 Targets JAG1 and Inhibits the Proliferation of Hepatocellular Carcinoma Cells
por: Tian, Junmei, et al.
Publicado: (2021)

[Retracted] MicroRNA‑143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer
por: Wu, Deyao, et al.
Publicado: (2023)

Upregulated microRNA-143 inhibits cell proliferation in human nasopharyngeal carcinoma
por: He, Benfu, et al.
Publicado: (2016)

Serum microRNA 143 and microRNA 215 as potential biomarkers for the diagnosis of chronic hepatitis and hepatocellular carcinoma
por: Zhang, Zhu-qing, et al.
Publicado: (2014)

Jagged2a-Notch Signaling Mediates Cell Fate Choice in the Zebrafish Pronephric Duct
por: Ma, Ming, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_qgfhfbhn6su18hjikvo94l3hgq