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Combination of Cordycepin and Apatinib Synergistically Inhibits NSCLC Cells by Down-Regulating VEGF/PI3K/Akt Signaling Pathway

BACKGROUND: The application of apatinib is immensely limited by its acquired drug resistance. This research investigates whether cordycepin, a component from Cordyceps could synergize with apatinib to improve its anticancer effect on non-small cell lung cancer (NSCLC) cells. METHODS: The NSCLC cell...

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Detalles Bibliográficos
Autores principales: Liao, Xiaozhong, Tao, Lanting, Guo, Wei, Wu, Zhuo-Xun, Du, Haiyan, Wang, Jing, Zhang, Jue, Chen, Hanrui, Chen, Zhe-Sheng, Lin, Lizhu, Sun, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505117/
https://www.ncbi.nlm.nih.gov/pubmed/33014856
http://dx.doi.org/10.3389/fonc.2020.01732