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Antiplatelet Effect of Carbon Monoxide Is Mediated by NAD(+) and ATP Depletion

OBJECTIVES: Carbon monoxide (CO) produced by haem oxygenases or released by CO-releasing molecules (CORM) affords antiplatelet effects, but the mechanism involved has not been defined. Here, we tested the hypothesis that CO–induced inhibition of human platelet aggregation is mediated by modulation o...

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Detalles Bibliográficos
Autores principales: Kaczara, Patrycja, Sitek, Barbara, Przyborowski, Kamil, Kurpinska, Anna, Kus, Kamil, Stojak, Marta, Chlopicki, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505148/
https://www.ncbi.nlm.nih.gov/pubmed/32787519
http://dx.doi.org/10.1161/ATVBAHA.120.314284