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lncRNA Xist Regulates Osteoblast Differentiation by Sponging miR-19a-3p in Aging-induced Osteoporosis

The switch between osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays a key role in aging-induced osteoporosis. In this study, miR-19a-3p was obviously downregulated in BMSCs from aged humans and mice. Overexpressed miR-19a-3p evidently reduced aging-induce...

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Detalles Bibliográficos
Autores principales: Chen, Shijie, Li, Yuezhan, Zhi, Shuang, Ding, Zhiyu, Huang, Yan, Wang, Weiguo, Zheng, Ruping, Yu, Haiyang, Wang, Jianlong, Hu, Minghua, Miao, Jinglei, Li, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505278/
https://www.ncbi.nlm.nih.gov/pubmed/33014522
http://dx.doi.org/10.14336/AD.2019.0724